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Creatine Monohydrate is a compound that is naturally made in our bodies to supply energy to our muscles. Creatine is
formed from the amino acids arginine, methione, and glycine through an involved chemical process. Creatine is
manufactured in the liver and may also be produced in the pancreas and kidneys. It is transported in the blood and taken
up by muscle cells, where it is converted to creatine phosphate, also called "phosphocreatine." This reaction involves the
enzyme creatine kinase which helps bond creatine to a high-energy phosphate group. Once the creatine is bound to a
phosphate group, it is permanently stored in a cell as phosphocreatine until it is used to produce chemical energy called
adenosine triphosphate (ATP). Once this is done, creatine can be released to spontaneously form creatinine, which is
then removed from the blood via the kidneys and excreted in the urine. In order to increase athletic performance and
boost lean body mass, creatine must be taken in concentrations which are not reasonably obtained from a whole food
diet.
Although creatine's role in the energy production process is its most notable trait, there is evidence that creatine can
stimulate muscle growth. It does this in a couple of different ways. By allowing you to perform more work as a result of
additional energy, increased protein synthesis is stimulated. Secondly, when an abundance of creatine phosphate is
stored n the muscle, the muscle will hold more water in its cells and become what is known as "volumized" or "superhydrated."
The more volumized a muscle is, it will promote the synthesis of protein as well as deter the breakdown of
protein. Volumizing the muscle will also create an environment where an increased level of Glycogen synthesis will take
place. Increased protein synthesis along with training will lead to muscle growth. There is also scientific evidence that
shows supplementation with creatine causes muscle tears to repair themselves quicker.
Creatine Monohydrate Benefits:
Helping build lean body mass, which allows greater force to be used
Providing energy so duration of exercise or work can be lengthened
Speeding recovery so exercise frequency can be increased
Promoting muscle growth by stimulating protein synthesis
Buffering lactic acid and improve exercise recovery time
Creatine Monohydrate should be taken in two phases: Loading Phase and Maintenance Phase. Creatine should be
taken with a high glycemic carbohydrate source like dextrose (also known as glucose), such as grape or orange juice to
load your muscles. Use 20-30 grams of creatine per day for a week (loading phase) and then cut back to 5-15 grams per
day (maintenance dose). If you're like most people, you'll notice a dramatic increase in size and strength. You'll get
better pumps, and your muscles will be noticeably stronger and firmer. For best results, take creatine immediately before
and after workouts.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
A.L. Green, et al., "Creatine Ingestion Augments Muscle Creatine Uptake and Glycogen Synthesis During Carbohydrate Feeding in Man," J. Physiol 491
(1996): p. 63-64
A. L. Green, et al., "Creatine Ingestion Augments Skeletal Muscle Creatine Accumulation During Creatine Supplementation in Man," Am., J. Physiol (in
Press 1997)
Gajja S.; Wyss, Markus . "Creatine and Creatine Kinase in Health and Disease" (2007) Series: Subcellular Biochemistry , Vol. 46 Salomons, (Eds.) 2007,
XVIII, 352 p., Hardcover ISBN: 978-1-4020-6485-2
Burke DG, Chilibeck PD, Parise G, Candow DG, Mahoney D, Tarnopolsky M (2003). "Effect of creatine and weight training on muscle creatine and
performance in vegetarians". Medicine and science in sports and exercise 35 (11): 1946–55.
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